Dean Office

Professor Dr. Abdul Matin

Dean

 Faculty of Natural and Health Sciences;

Chairperson Department of Biological Sciences


Designation

Dean Faculty of Natural and Health Sciences; Chairperson Department of Biological Sciences

Email Address

This email address is being protected from spambots. You need JavaScript enabled to view it.This email address is being protected from spambots. You need JavaScript enabled to view it., This email address is being protected from spambots. You need JavaScript enabled to view it.

Qualification

PhD Medical Microbiology

Research Interests

Infectious diseases

Microbial pathogenesis

Proteomics

Parasite-pathogen interactions

Blood-brain barrier

Nanomedicine

Cell Signaling

Epidemiology

Brief Description

Dr. Abdul Matin completed his PhD in Medical Microbiology from Birkbeck College, University of London followed by a Postdoctoral Research Fellowship (Immunopharmacology) from School of Medicine, Southampton University Hospital, Southampton, United Kingdom. Latter on, he worked as Associate Professor at Majmaah (Saudi Arabia) and Nizwa University (Sultanate of Oman). Currently, he is a Professor at department of Biological Sciences, University of Baltistan, Skardu, Gilgit-Baltistan, Pakistan.

My Publications

2021

  1. Alouffi, A. S., Turki M. Dawoud, T. M., Almaary, K. S., Mubarak, A. S., JarAllah, K., Matin, A. First report of detection of IgA anti-Acanthamoeba antibodies among Saudi population and amoeba isolation from their surroundings. Malaysian Society of Parasitology and Tropical Medicine. 38(1): 73-80.

 

2020

  1. Rafique, MW., Manan, T.,  Slaeem, S., Matin, A., and Ahmad, I. Type 1 fimbriae and motility play a pivotal role during interactions of Salmonella typhimurium with Acanthamoeba castellanii (T4 Genotype). Current Microbiology. 77: 836–845.
  2. Sirajuddin, M., Tariq, M., Ali, S.,McKeed, V., Matin, A. Synthesis, characterization and biological screenings of 5-coordinated Organotin (IV) complexes based on carboxylate ligand. Journal of Molecular Structure. 1206:127683.
  3. Matin, A. Acanthamoeba; a potential reservoir for environmental transmission of COVID-19 with public health significance: pros and corns. The Open Microbiology Journal, 14; 130-131.

 

2019

  1. Matin, A., Brief review of anti-Brucella antibodies among Saudi population: Prevalence prospective. CPQ Microbiology. 3 (4): 1-5.

 

2018

  1. Gil, A., Rafique, MW., Manan, T., Slaeem, S., Römling, U., Matin, A., and Ahmad., I. The cellulose synthase BcsA plays a role in interactions of Salmonella typhimurium with Acanthamoeba castellanii genotype T4. Parasitology Research. 117 (7); 2283-2289.
  2. Tanveer. T., Nawaz, S and Matin. A. Therapeutic potential of folk plants used against pathogenic and opportunistic free living amoeba (Acanthamoeba, Balamuthia and Naegleria); a review. International Journal of Cell Science and Molecular Biology. 4 (1); 1-13.
  3. Matin. A. Nawaz S. and Jung, S-Y. Effect of macrophage alone or primed with cytokines on Balamuthia mandrillaris interactions with human brain microvascular endothelial cells in vitro. Pakistan Journal of Pharmaceutical Sciences. 31(6): 2553-2559.

2017

  1. Tanveer, T., Hameed, A., Dukhyil A. A., Alaidarous, M., Matin, A. Isolation of thermotolerant pathogenic Naegleria australiensis from diverse water resources including household drinking water in Pakistan. Acta Protozoologica. 56: 321-326.
  2. Matin, A. Primary amebic meningoencephalitis; a new emerging public health threat by Naegleria fowleri in Pakistan. Journal of Pharmaceutical Research and Drug Design. 1: 1-3.

2016

  1. Imran, M., Muazzam, AG., Habib, A and Matin, A. Synthesis, characterization and amoebicidal potential of locally synthesized TiO2 nanoparticles against pathogenic Acanthamoeba trophozoites in vitro. Journal of Photochemistry & Photobiology B: Biology. 159: 125-132.
  2. Sohaib HM, Nawaz S, and Matin A., Methanolic extracts of Peganum harmala exhibit potent activity against Acanthamoeba castellanii cysts and its encystment in vitro. Pakistan Journal of Pharmaceutical Sciences 29(6):1993-1996.

2015

  1. Tanveer, T., Hameed, A., Gul, A and Matin, A. Quick survey for detection, identification and characterization of Acanthamoeba genotypes from some selected soil and water samples in Pakistan. Annals of Agricultural and Environmental Medicine. 22 (2): 232-235.
  2. Ajmal, M, Yunus, U,   Matin, A, Haq N. Synthesis, characterization and in vitro evaluation of methotrexate conjugated fluorescent carbon nanoparticles as drug delivery system for human lung cancer targeting. Journal of Photochemistry & Photobiology B: Biology. 153: 111-120.

2014

  1. Saeed A, Mahesar PA, Zaib S, Khan MS, Matin A, Shahid M, Iqbal J. Synthesis, cytotoxicity and molecular modelling studies of new phenylcinnamide derivatives as potent inhibitors of cholinesterases. European Journal of Medicinal Chemistry, 78: 43-53.
  2. Erben F, Michalik D, Feist H, Kleeblatt D,  Hein M, Matin A, Iqbal J, Langer P. Synthesis and antiproliferative activity of (Z)-1-glycosyl-3-(5-oxo-2-thioxoimidazolidin-4-ylidene)indolin-2-ones and (Z)-3-(2-glycosylsulfanyl-4-oxo-4,5-dihydro-thiazol-5-ylidene)indolin-2-ones. RSC Advances, 4: 10879-10893.
  3. Kleeblatt D, Cordes CA, Lebrenz P, Hein M, Feist H, Matin A, Raza R, Iqbal J, Munshi O, Rahman Q, Villinger A, and Langer P.  Synthesis and Antiproliferative Activity of N-Glycosyl-3,3-diaryloxindoles. RSC Advances. 4: 22828-22839.
  4. Matin. A. Jung, S-Y and Nawaz S. In vitro assessment of cytokines interactions with Balamuthia mandrillaris using human brain microvascular endothelial cells. Pakistan Journal of Pharmaceutical Sciences 27(1):107-113.

2013

  1. Erben F, Kleeblatt D, Sonneck M, Hein M, Feist H, Fahrenwaldt T, Fischer C, Matin A, Iqbal J, Plötz M, Eberle J and Langer P. Synthesis and antiproliferative activity of selenoindirubins and selenoindirubin-N-glycosides. Organic & Biomolecular Chemistry, 11(24):3963-3978.
  2. Shoaib. H.M, Muazzam. A.G, Mir. A, Jung. S-Y and Matin. A. Evaluation of inhibitory potential of some selective methanolic plants extracts on biological characteristics of Acanthamoeba castellanii using human corneal epithelial cells in vitro. Parasitology Research. 112 (3): 1179-1188.
  3. Tanveer T, Hameed A, Muazzam. A.G, Jung S-Y, Gul A and Matin A. Isolation and molecular characterization of potentially pathogenic Acanthamoeba genotypes from diverse water resources including household drinking water from Khyber Pakhtunkhwa, Pakistan. Parasitology Research. 112 (8): 2925-2932.
  4. Iqbal J, Saeed A, Raza R, Matin A, Hameed A, Furtmann N, Lecka J, Sévigny J,  Bajorath J. Identification of Sulfonic Acids as Efficient Ecto-5'-Nucleotidase Inhibitors. European Journal of Medicinal Chemistry. 70: 685-691.

2012

  1. Raza. R, Matin. A, Sarwar. S, Barsukova-Stuckart. M, Ibrahim. M, Kortz. U and Iqbal. J. Polyoxometalates as potent and selective inhibitors of alkaline phosphatases with profound anticancer and amoebicidal activities. Dalton Transaction. 41(47):14329-14336.
  2. Kim. JH, Matin. A, Shin. HJ, Park. H, Yoo. KT, Yuan. XZ, Kim. KS, Jung. SY. Functional roles of mannose-binding protein in the adhesion, cytotoxicity and phagocytosis of Acanthamoeba castellanii. Experimental Parasitology. 132: 287-292.
  3. Matin A, Mehmood K, Jung S-Y. Impact of macrophages on Balamuthia mandrillaris virulence properties using human brain microvascular endothelial cells in vitro. Retrovirology. 9(1): 38.
  4. Matin A, Ismail M, Mehmood K. Acanthamoeba castellanii. antibody prevalence among diverse tribal Pakistani population. Retrovirology. 9(1): 47.

2011

  1. Matin. A, and Jeong. S-Y. Phospholipases activities in the clinical and environmental isolates of Acanthamoeba. Korean Journal of Parasitology. 49:1-8.
  2. Matin. A, and Jeong. S-            Y. Interaction of Escherichia coli K1 and E. coli K5 with Acanthamoeba castellanii trophozoites and cysts. Korean Journal of Parasitology. 49 (4): 349-356.

2009

  1. Brindley. N, Matin. A, and Khan. N. A. Acanthamoeba castellanii: High antibody prevalence in racially and ethnically diverse populations. Experimental Parasitology, 121: 254-256.

2008

  1. Matin. A, Siddiqui. R, Jayasekera. S, and Khan. N. A. The increasing importance of Balamuthia mandrillaris. Clinical Microbiology Reviews, 21(3): 435-448.
  2. Matin. A, and Khan. N. A. Demonstration and partial characterization of ecto-ATPase activity in Balamuthia mandrillaris and its possible role in host cell interactions. Letters in Applied Microbiology, 47: 348-354.

2007

  1. A, Jeong. S. R, Kim. K. S, Stins. M, and Khan. N. A. Balamuthia mandrillaris interactions with the human brain microvascular endothelial cells in vitro. Journal of Medical Microbiology, 56: 1110-1115.
  1. Matin. A, Jeong. S. R, Stins. M, and Khan. N. A. Effects of human serum on Balamuthia mandrillaris interactions with human brain microvascular endothelial cells. Journal of Medical Microbiology, 56: 30-35.
  2. Jung. S-Y, Matin. A, Kim. K. S, and Khan .N. A. The capsule plays an important role in Escherichia coli K1 interactions with Acanthamoeba. International Journal of Parasitology. 37: 417-423.
  1. R, Matin. A, Warhurst. D, Stins. M, and Khan. N. A. Effect of antimicrobial compounds on Balamuthia mandrillaris encystment and human brain microvascular endothelial cell cytotoxicity. Antimicrobial Agents and Chemotherapy. 51: 4471-4473.

2006

  1. A, Stins. M, Kim. K. S, and Khan. N. A. Balamuthia mandrillaris exhibit metalloprotease activities. FEMS Immunology and Medical Microbiology 47: 83-91.
  2. A, Jeong. S. R, Faull. J, and Khan. N. A. Evaluation of prokaryotic and eukaryotic cells as food source for Balamuthia mandrillaris. Archive of Microbiology 186: 261-271.

2005

  1. R, Matin. A, Alsam. S, Sissons. J, Mahsood. A. H, and Khan. N. A. Acanthamoeba isolates belonging to T1, T2, T3, T4 but not T7 encyst in response to increased osmolarity and cysts do not bind to human corneal epithelial cells. Acta Tropica 95(2):100-108.
  2. S, Matin, A. Sissons, J. Mahsood. A. H, and Khan. N. A. Balamuthia mandrillaris stimulates interleukin-6 release in primary human brain microvascular endothelial cells via a phosphatidylinositol 3- kinase-dependent pathway. Microbes & Infection 7(3): 1345-1351.

2002

  1. A, Khan. M. A, Ashraf. M, and Qureshi. R. A. Pollen Fertility Investigation of Medicinal Plants of the Himalayan Region, Shogran Valley District Mansehra Pakistan. Hamdard Medicus 25(1): 78-82.
  2. A, Khan. M. A, Ashraf. M, and Qureshi. R. A. Traditional Use of Shrubs and Trees of Himalayan Region, Shogran Valley Pakistan. Hamdard Medicus 25(2): 50-56.

2001

  1. A, Khan. M. A, Ashraf. M, and Qureshi. R. A. Traditional Use of Herbs, Shrubs and Trees of Himalayan Region, Shogran Valley District Mansehra, Pakistan. Pakistan Journal of Biological Sciences 4(9): 1101-1107.

 

Books

  1. Matin, A. Pathogenesis of Balamuthia Amoebic Encephalitis. Lambert Academic Publications.

 

Gene Bank Submissions:

In total 43 partial gene sequences of free living amoeba (Acanthamoeba sp., Naegleria sp. and Vahlkampfia sp.) were reported for the first time from Pakistan including 17 novel sequences after my name.

 

Novel Partial Gene Sequences (17) published after my name.

  • Tanveer, T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Isolation and molecular identification of free-living amoeba from natural resources of Pakistan. GeneBank Accession No: KF018478, KF018479
  • Tanveer, T., Hameed, A., Jung,S.Y., Gul, A. and Matin, A. 2013. Molecular identification and characterization of Acanthamoeba species in natural resources of Pakistan. GeneBank Accession No: KC493774, KC493776
  • Tanveer, T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Isolation and molecular characterization of free living amoeba from environmental sources of Pakistan. GeneBank Accession No: KC874856, KC874857
  • Tanveer, T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Isolation and molecular identification of free-living amoeba from natural resources of Pakistan. GeneBank Accession No: KF018478, KF018479
  • Tanveer, T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Molecular identification and characterization of Acanthamoeba species in natural resources of Pakistan. GeneBank Accession No: KF035055, KF035056
  • Tanveer, T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Isolation and genotyping of free living amoeba from Pakistan. GeneBank Accession No: KF234561, KF234562    
  • Tanveer, T., Hameed, A., Jung,S.Y., Gul, A. and Matin, A. 2013. Molecular identification and characterization of Acanthamoeba species in natural resources of Pakistan. GeneBank Accession No: KC493774, KC493776, KC493777
  • Tanveer, T., Hameed, A., Muazzam, A.G., Zafar, B.U. and Matin, A. 2013.  Isolation of free-living amoeba from Azad Jammu Kashmir, Pakistan. GeneBank Accession No: KF442971, KF442972

 

The remaining 26 partial gene sequences

  • Tanveer, T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Identification of Acanthamoeba from soil and water sources in Islamabad,Pakistan. GeneBank Accession No: KC778188, KC778190
  • Tanveer,T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Isolation and genotyping of environmental sources in Karachi, Pakistan. GeneBank Accession No: KC778189
  • Tanveer,T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013.  Genotyping of free living amoeba from water resources in Karachi, Pakistan. GeneBank Accession No: KC778187
  • Tanveer,T., Hameed,A., Muazzam,A.G., Gul,A. and Matin, A. 2013. Isolation and genotyping of Acanthamoeba from soil samples in Lahore, Pakistan. GeneBank Accession No: KC778186
  • Tanveer,T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013.  Isolation and molecular characterization of free living amoeba from environmental sources of Pakistan. GeneBank Accession No: KC820644, KC820645, KC820646, KC820647, KC820648
  • Tanveer,T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Isolation and molecular identification of free-living amoeba from natural resources of Pakistan. GeneBank Accession No: KF018477, KF018480, KF018481
  • Tanveer,T., Hameed, A., Muazzam, A.G., Gul, A. and Matin, A. 2013. Molecular identification and characterization of Acanthamoeba species in natural resources of Pakistan. GeneBank Accession No: KF035057,
  • Tanveer,T., Hameed, A., Muazzam, A.G., Zafar, B.U. and Matin, A. 2013.  Isolation of free-living amoeba from Azad Jammu Kashmir, Pakistan. GeneBank Accession No: KF153929, KF153930, KF153931, KF153932, KF153933, KF153934, KF153935
  • Tanveer,T., Hameed, A., Jung, S.Y., Gul, A. and Matin, A. 2012. Molecular identification and characterization of Acanthamoeba species in natural resources of Pakistan. GeneBank Accession No: KC203588, KC203589, KC203590, KC203591, KC203592, KC493773, KC493775