dr nusrat hussain

Name

Nusrat Hussain

Title

Dr.

Department

Chemistry

Short introduction

Dr. Nusrat Hussain got his Ph.D degree in Organic Chemistry from H.E.J. Research Institute of Chemistry, University of Karachi.  He was selected for Talented Young Scientist Program (TYSP) by Ministry of Science and Technology (MOST) China. He joined Hunan University of Chinese Medicine, Changsha, Hunan, China for postdoctoral research and stayed there for one year. On his returned he joined University of Baltistan, Skardu as an assistant Professor. His research interests are related to isolation and characterization of bioactive natural products, structural transformation of natural products and Bio-fabrication of gold and silver nanoparticles. He has published 20 research articles in international impact factor journals.

Keywords

Medicinal Chemistry, Natural Products, Chromatography, Spectroscopy

RESEARCH PROJECTS / FOCUS AREAS

Title and description of research projects/focus areas

  • Isolation and identification of bioactive natural products.
  • Structural transformation of natural products.
  • Bio-fabrication of gold and silver nanoparticles
  • Organic synthesis, development of new synthetic methodologies.

 

PUBLICATIONS

·         Ting Zeng, YanRan Tang, Bin Li, Shumaila Tasneem, Nusrat Hussain, Cai-Yun Peng, Shu-Jin He and Wei Wang, Chemical characterization of constituents from Polygonatum cyrtonema Hua and their cytotoxic and antioxidant evaluation, Natural Product Research, 2019, (Online). (I.F. 1.999)

·         Nusrat Hussain, Abdul Hameed, Malik Shoaib Ahmad, Mujeeb-ur-Rehman, Samar Yousuf, Zulfiqar Ali, M. Hafizur Rahman, M. Iqbal Choudhary, New iridoids from Lyonia ovalifolia and their anti-hyperglycemic effects in mice pancreatic islets, Fitoterapia, 2018, 131, 168-173. (I.F. 2.431)

·         Yongbei Liu, Yupei Yang, Shumaila Tasneem, Nusrat Hussain, Muhammad Daniyal, Hanwen Yuan, Qingling Xie, Bin Liu, Jing sun, Yuqing Jian, Bin Li, Shenghuang Chen, Wei Wang, Lignans from Tujia Ethnomedicine Heilaohu: Chemical characterization and evaluation of their cytotoxicity and antioxidant activities, Molecules, 2018, 23(9), 2147. (I.F. 3.060)

·         Rabia Farooq, Nusrat Hussain, Sammer Yousuf, Atia-tul-Wahab, Malik Shoaib Ahmad, Atta-ur-Rahman, M. Iqbal Choudhary, Microbial transformation of mestanolone by Macrophomina phaseolina and Cunninghamella blakesleeana and anticancer activities of its transformed products, RSC Advances, 2018, 8, 21985-21992. (I.F. 3.05)

·         Abdul Hameed, M. Hafiz ur Rahman, Nusrat Hussain, Sayed Ali Raza, MujeebRehman, Sajda Ashraf, Zaheer-Ul-Haq, Faisal Khan, Ghulam Abbas, M. Iqbal Choudhary, Eriodictyol stimulates insulin secretion through cAMP/PKA signaling pathway in mice islets, European Journal of Pharmacology, 2018, 820, 245-255. (I.F. 3.170)

·         Yan-jiao Chen, Liang Na, Jialong Fan, Jianping Zhao, Nusrat Hussain, Yu-qing Jian, Hanwen Yuan, Bin Li, Bin Liu, M. Iqbal Choudhary, Ikhlas Khan, Wei Wang, “Seco-dammarane triterpenoids from the leaves of Cyclocarya paliurus”, Phytochemistry, 2018, 145, 85-92. (I.F. 2.905)

·         Yang Chen, Jianping Zhao, YixingQiu, Hanwen Yuan, Shabana I. Khan, Nusrat Hussain, M. Iqbal  Choudhary, Feng Zeng, De-An Guo, Ikhlas A. Khan, Wei Wang, “Prenylated flavonoids from the stems and roots of Tripterygium wilfordii”, Fitoterapia, 2017,119, 64-68. (I.F. 2.431)

·         Nusrat Hussain, AchyutAdhikari, Malik Shoaib Ahmad, Atia-tul- Wahab, Meher Ali, M. Iqbal Choudhary, “Two new prenylated flavonoids from the roots of Berberis thunbergii DC”, Natural Product Research, 2017, 31(7), 785-790. (I.F. 1.999)

·         Malik Shoaib Ahmad, Rabia Farooq, Nusrat Hussain, Atia-tul-Wahab, Atta-ur-Rahman, M. Iqbal Choudhary, “Three new analogues of androgenic drug mesterolone through biotransformation with Cunninghamella blakseleeana”, Journal of Molecular Catalysis B: Enzymatic, 2016, 133(S1), S395-S399. (I.F. 2.45)

·         Muhammad Ibrahima, Iqbal Hussain, Nusrat Hussain, Amjad Hussain, Shabbir Hussain, “A New Guaianolide from Medicinal Plant Amberboa ramosa”, Natural Product Research, 2016, 30(1), 110-114. (I.F. 1.999)

·         Bakhat Ali, Muhammad Ibrahim, Muhammad Imran, Haq Nawaz, Saleem Jan, Nusrat Hussain, Muhammad Khalid, Iqbal Hussain, “Pakistamide C, a New Sphingolipid from Abutilon pakistanicum”, Brazilian Journal of Pharmacognosy, 2014, 24(2), 277-281. (I.F. 1.754)

·         Ala Uddin, Ghias Uddin, Nusrat Hussain, Ajmal Khan, Inamullah Khan, Anwar Ali Shad and Muhammad Iqbal Choudhary, “Bioassay-guided Isolation of New Antitumor Agent from Ficus faveolata (Wall. exMiq.)”, Cancer Science & Therapy, 2013, 5(11), 404-408. (I.F. 1.64)

·         Muhammad Ibrahim, Iqbal Hussain, Muhammad Imran, Nusrat Hussain, Amjad Hussain, Tooba Mahboob, Corniculatin A, A New Flavonoidal Glucoside from Oxalis corniculata”, Brazilian Journal of Pharmacognosy, 2013, 23(4), 630-634. (I.F. 1.754)

·         Muhammad Ibrahim, Tahir Farooq, Nusrat Hussain, Amjad Hussain, Tahsin Gulzar, Iqbal Hussain, Muhammad Sajid Akash and Fouzia Sultana Rehmani, “Acetyl and Butyryl Cholinesterase Inhibitory Sesquiterpene Lactones from Amberboa ramosa”, Chemistry Central Journal. 2013, 7, 116. (I.F. 2.094)

·         Muhammad Ibrahim, S. Ambreen, Amjad Hussain, Nusrat Hussain, Maria yousuf, and Fouzia Sultana Rehmani, “Phytochemical Investigation on Eucalyptus globules Labill”, Asian Journal of Chemistry, 2014, 26(4), 1015-1018. (I.F. 1.20)

·         Ala Uddin, Nusrat Hussain, Ghias Uddin and Mohammad Iqbal Choudhary, “Ficusonic Acid: A New Cytotoxic Triterpene Isolated from Maytenus royleanus(Wall. ex M. A. Lawson) Cufodontis”, Journal of Brazilian Chemical Society, 2013, 24 (4), 663-668. (I.F. 1.44)

·         M. Iqbal Choudhary, Amjad Hussain, Nusrat Hussain, Achyut Adhikari, Bishnu P. Marasini, Samina A. Sattar, Atia-tul-Wahab, Syed A. Majid Ayatollahi, Atta-ur-Rahman, “Anticancer and α-Chymotrypsin Inhibiting Diterpenes and Triterpenes from Salvia leriifolia”, Phytochemistry Letters, 2013, 6, 139-143. (I.F. 1.338)

·         M. Iqbal Choudhary, Achyut Adhikari, Saima Rasheed, Nusrat Hussain, Bishnu P. Marasini, , Waqar Ahmad Kaleem, and Atta-ur-Rahman,“Cyclopeptide Alkaloids of Zizyphus oxyphylla Edgew Novel Inhibitors of a-Glucosidase Enzyme and Protein Glycation”, Phytochemistry Letters, 2011, 4, 404–406. (I.F. 1.338)

·         Muhammad Nisar, Waqar Ahmad Kaleem, Achyut Adhikari, Zulfiqar Ali, Nusrat Hussain, Inamullah Khan, and M. Iqbal Choudhary, “Stereochemistry and NMR Data Assignment of Cyclopeptide Alkaloids from Zizyphus oxyphylla”, Natural Product Communications, 2010, 5(8), 1205-1208. (I.F. 1.01)

·         Zahid Hussain, Nusrat Hussain, Atia-tul-Wahab, Shabbir Hussain, M. Iqbal Choudhary, Seven New Transformed Metabolites of Drostanolone Heptanoate by using Beauveria bassiana and Macrophomena phaseolina Cell Suspension Cultures, RSC Advances (Accepted). (I.F. 3.05)

·         Book Chapters Published:

·         Yongbei Liu, Yupei Yang, Nusrat Hussain, Muhammad Daniyal, Hanwen Yuan, Shenghuang Chen, Wei Wang, Lignans from Tujia Ethnomedicine Heilaohu: Chemical characterization and evaluation of their cytotoxicity and antioxidant activities, Lignans David Barker (Ed.) 2019, MDPI Publishers, Basel, Switzerland.

 

ACHIEVMENTS/ AWARDS

·         Recipient of Talented Young Scientist Program (TYSP) Post-Doc fellowship by Ministry of Science and Technology (MOST) P. R. China.

·         ICCBS Postgraduate Research Fellowship awarded by H.E.J Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi.

MEMBERSHIPS

1.      Member of Chemical Society of Pakistan.

2.      Member of the Asian Society of Pharmacognosy.

3.      Reviewer in the Journal “Fitoterapia” (Elsevier).

4.      Reviewer in the Journal “Natural Products Research” (Taylor & Francis).

Email

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Lab/Office Address

Room # 116, Department of Chemistry, University of Baltistan Skardu, main campus Hussainabad, Skardu, GB, Pakistan. 16100

Lab/Office Telephone